Publications

Lipoxin A4 activates Nrf2 expression and mitigates hyperglycaemia-induced impairment of myogenesis and rescues damage to mitochondria

Lipoxin A4 restores myogenesis under hyperglycaemic stress by activating Nrf2 signaling. It reduces oxidative stress and preserves mitochondrial integrity.

Journal of Physiology and Biochemistry

Arachidonic Acid Protects Skeletal Muscle Against Hyperglycaemia-Induced Muscle Atrophy by Modulating Myogenesis and Regulating KLF15 Expression in C57Bl/6 Mice

Arachidonic acid protects against diabetes-induced muscle atrophy in mice. It restores myogenesis and suppresses KLF15-mediated catabolic pathways.

The FASEB Journal

Mitigation of chronic glucotoxicity-mediated skeletal muscle atrophy by arachidonic acid

Arachidonic acid reverses glucotoxicity-induced muscle damage in vitro. It reduces inflammation and restores protein synthesis in muscle cells.

Life Sciences

Quercetin and Kaempferol Mitigate Endotoxin-Induced Skeletal Muscle Wasting by Inhibiting KLF15 Expression and Restoring the Antioxidant System

Quercetin and kaempferol reduce endotoxin-induced muscle wasting. They suppress inflammation, oxidative stress, and restore mitochondrial function.

The FASEB journal

The elusive role of myostatin signaling for muscle regeneration and maintenance of muscle and bone homeostasis

This review highlights the role of myostatin in muscle regeneration and disease. It discusses therapeutic targeting for muscle-wasting conditions.

Osteoporosis and Sarcopenia

Unlocking the Potential of Obestatin: A Novel Peptide Intervention for Skeletal Muscle Regeneration and Prevention of Atrophy

Obestatin promotes myogenesis and prevents muscle atrophy via GPR39 signaling. It modulates autophagy and enhances muscle regeneration pathways.